New technology can feel like a mental leap. Validation can seem daunting. But by partnering with Base Pair Biotechnologies the hard work is already done — through better technology, our expertise and yours.
All aptamer pricing includes a quantitative characterization of aptamer affinity (Kd determination). Typically, smaller targets will be validated using microscale thermophoresis (MST). For larger targets, surface plasmon resonance (SPR) or Backscattering Interferometry (BSI) will be used.
With extensive experience in the field, our researchers have fine-tuned these processes to accurately predict bio-molecular interactions and binding response. Aptamer production is inherently reliable and the product is stable throughout transport and storage. These factors combine to deliver reagents that don’t suffer the manufacturing and lot-to-lot variability of antibodies. Validated aptamers that are shipped to you arrive with their binding capacity intact.
We also offer contract MST, SPR and BSI services and Kd determination for any biological system (antibody:protein, protein:protein, etc) on a fee for service basis.